A pair of differences is a \emph{related differential} for a linear layer if, for every coordinate at both the input and the output, at least one of the two values vanishes or the two values coincide. Related differentials underlie the zero-difference attack on AES of Bardeh and Rijmen, and the question of which maximum distance separable (MDS) matrices admit them was raised by Daemen and Rijmen, who showed that every circulant MDS matrix does while some Hadamard ones do not. In earlier work the MDS matrices over admitting related differentials were characterized by fifteen explicit equations. In this paper we settle the case completely: an MDS matrix over admits a related differential if and only if at least one of explicit polynomial equations in the nine free entries of its reduced form holds. The equations, quadratic and cubic, are pairwise distinct, irreducible and pairwise coprime, and fall into orbits under the natural symmetries. We further determine the structure of the equation set: the fifteen equations of the case are exactly the points of , while the equations span a -dimensional -space, satisfy exactly additive relations, and contain exactly pairs that can never hold simultaneously on an MDS matrix. The discarded zero patterns split into whose determinant condition is equivalent to the failure of MDS-ness and vacuous cases. Over , the smallest field carrying MDS matrices, exhaustive enumeration shows that there are exactly reduced MDS matrices; each satisfying exactly of the equations and each equation being satisfied by exactly matrices; in particular every MDS matrix over admits a related differential. Over we exhibit an explicit MDS matrix admitting none. All results are verified by exact computation against an independent exhaustive search.